体外测定了水溶性壳聚糖及其氨化衍生物对硬脂酸钠、十二烷基硫酸钠的结合能力及其影响因素。结果表明,水溶性壳聚糖结合硬脂酸钠、十二烷基硫酸钠的能力主要取决于其阳离子化程度。修饰后的壳聚糖对硬脂酸钠、十二烷基硫酸钠结合能力的增强,说明引入更多的胺基或铵基有利于对硬脂酸钠、十二烷基硫酸钠的结合,氨基上烷基与硬脂酸钠、十二烷基硫酸钠碳链之间也应当产生疏水相互作用。 In vitro, the binding ability of water-soluble chitosan and its derivatives to sodium stearate and sodium lauryl sulfate and their influencing factors were determined. The results showed that the ability of water-soluble chitosan to bind sodium stearate and sodium lauryl sulfate mainly depends on its degree of cationization. Modified chitosan on sodium stearate, sodium lauryl sulfate binding capacity increased, the introduction of more amino or ammonium group is conducive to the combination of sodium stearate, sodium lauryl sulfate, Amino-alkyl and sodium stearate, sodium lauryl sulfate should also produce a hydrophobic interaction between carbon chains.