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卵巢癌是妇科常见恶性肿瘤之一,约75%的患者在诊断时已属晚期,虽然在手术、化疗和靶向治疗等方面有了很大进步,但是总的5年生存率仍然停留在30%左右,其病死率位居妇科肿瘤之首,严重危害女性健康。目前卵巢癌缺乏行之有效的筛查手段,但是卵巢癌在病因学方面取得的研究进展,使预防卵巢癌成为可能。已有部分国家和地区的妇科肿瘤专家及病理学专家提倡对因绝经前良性病变女性或乳腺癌、卵巢癌高危女性(BRCA1/2突变阳性)需行全子宫切除术,同时行双侧输卵管切除术,成为降低
Ovarian cancer is one of the common gynecological malignancies. About 75% of the patients are already diagnosed late. Although there has been great progress in surgery, chemotherapy and targeted therapy, the overall 5-year survival rate remains at 30 % Or so, the highest rate of fatality in gynecological tumors, seriously endangering women’s health. At present, ovarian cancer lacks an effective screening method, but the progress made in the etiology of ovarian cancer has made it possible to prevent ovarian cancer. Some gynecologic oncologists and pathologists in some countries and regions have advocated hysterectomy for women with benign premalignant pathological changes or women at high risk of ovarian cancer (BRCA1 / 2 mutation positive), and bilateral salpingo-tubal resection Surgery, become reduced