论文部分内容阅读
目的：为探讨糖尿病胃轻瘫（ＤＧＰ）的发病机理及西沙必利对ＤＧＰ的治疗作用。方法：应用ＷＤＬ－２０００ 型胃动力诊断仪对４０ 例２ 型糖尿病患者进行胃动力检测并与３０ 例健康人作对照。同时观察西沙必利治疗前后胃动力变化和血糖对胃动力的影响。结果：显示４０ 例糖尿病患者胃动力异常的血糖值与胃动力正常的血糖值有显著性差异（Ｐ＜ ０．００１）。胃动力异常检出率为７２．５％ ，与健康人相比具有显著性意义（Ｐ＜ ０．００５）。经西沙必利治疗后胃动力恢复正常率为７５．８％ ，且治疗前后的血糖值具有显著差异（Ｐ＜ ０．００１）。结论：观察说明胃动力异常可能为ＤＧＰ的发病机理，且血糖值升高是引起胃动力异常的一重要因素
Objective: To investigate the pathogenesis of diabetic gastroparesis (DGP) and the therapeutic effect of cisapride on DGP. Methods: The gastric motility of 40 patients with type 2 diabetes mellitus was measured by WDL-2000 gastric motility diagnostic instrument and compared with 30 healthy people. At the same time observe cisapride treatment of gastric motility changes and blood glucose on gastric motility. Results: There was a significant difference (P <0.001) between the blood glucose level of gastric dysmotility and the normal gastric motility in 40 patients with diabetes mellitus. The detection rate of abnormal gastric motility was 72.5%, which was significantly higher than that of healthy people (P <0.005). The normal rate of gastric motility recovery after cisapride treatment was 75.8%, and there was a significant difference between before and after treatment (P <0.001). Conclusion: The observation shows that abnormal gastric motility may be the pathogenesis of DGP, and elevated blood glucose levels is an important factor in gastric motility abnormalities