白塞(Behcet)综合征是一种以眼、皮肤粘膜、关节、血管、胃肠道和神经等多系统损害为特征的疾病。本病在地中海地区和日本最为流行。在美国成人病例少见,已有少数儿童病例报道。白塞综合征由于缺乏特殊症状、体征和实验室特征,故诊断困难。在一次自塞综合征的国际专题会议上仍不能一致通过本病的诊断标准。有些研究者提议,原有的3个标准(口疮性口炎、生殖器溃疡和葡萄膜炎)中仅有2个为诊断所必须;而Mason和Barnes提出了一组复杂的4条主要标准(颊粘膜溃疡、生殖器溃疡、眼和皮肤损害)和6条次要标准(胃肠 Behcet’s syndrome is a disease characterized by multiple system lesions of the eye, skin and mucous membranes, joints, blood vessels, gastrointestinal tract and nerves. The disease is most prevalent in the Mediterranean and Japan. In the United States, rare adult cases have been reported in a small number of children. Behcet’s syndrome is diagnosed because of the lack of specific symptoms, signs and laboratory characteristics. In a self-Cypriot syndrome international symposium still can not unanimously adopted the diagnostic criteria of this disease. Some researchers propose that only two of the three original criteria (aphthous stomatitis, genital ulcers and uveitis) are required for diagnosis; Mason and Barnes proposed a complex set of four major criteria Mucosal ulcers, genital ulcers, eye and skin lesions) and six secondary criteria (gastrointestinal