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国内应用乙胺嘧啶食盐(下简称乙盐)预防间日疟,已在各地取得了较好的效果。但在大剂量(平均每人每日6.25mg连续服用120天)连续服用的后期、可在部分人群中产生巨幼红细胞性贫血的付作用。为了减少付作用、找出乙盐预防服药的合适剂量和服用时间、我们今年以较低剂量、对其预防疟疾的效果及付作用进行了继续观察、现将结果报告如下:
Domestic application of pyrimethamine salt (hereinafter referred to as salt) to prevent vivax malaria, has achieved good results in various places. However, high doses (an average of 6.25mg per person per day for 120 consecutive days of taking the latter part of the continuous take, in some people can produce megaloblastic anemia in payment. In order to reduce the role of pay, to find the appropriate dose of salt prevention and medication taking time, we are at a lower dose this year, the effect of malaria prevention and treatment were observed, the results are reported as follows: