以取代芳醛和丙酮为原料,合成了7个取代亚苄基丙酮,研究了不同取代芳醛与丙酮之间的Claisen-Schmidt缩合反应的电子效应。产物结构经IR及1HNMR鉴定,并用HPLC测定了含量。研究取代基电子效应对缩合反应影响的实验表明,含推电子取代基芳醛所需的缩合反应温度较高,而含吸电子取代基芳醛的缩合反应在较低温度下就可以进行。 Using substituted aromatic aldehydes and acetone as raw materials, 7 substituted benzylidene acetone was synthesized and the electronic effect of Claisen-Schmidt condensation reaction between different substituted aryl aldehydes and acetone was studied. The product structure was identified by IR and 1HNMR, and the content was determined by HPLC. Experiments on the effect of substituent electronic effects on the condensation reaction showed that the condensation reaction temperature required for the inclusion of an electron-donating aromatic aldehyde is relatively high, whereas the condensation reaction involving an electron-withdrawing substituent aromatic aldehyde can be carried out at a relatively low temperature.