论文部分内容阅读
本文对101例健康人包括中青年组(20～40岁)31例,老年前期(45～59岁)31例,老年组(≥60岁)39例分别作RP_1,RP_2、RP(2-1)、RP(μ-s)、PEP、SOD、LPO、T_3、T_4、TSH、Zn、CuA、Ig、IgG和IgM等15项衰老生物标记测定。得出SOD中青年组1323±149(sigma U/gHb),随增龄而减少至老年组1184±103(sigma U/gHb)(P<0.01),不受性别影响,可作衰老敏感标记;RP(2-1)老年组32.95±13.53(ms)较中青年组44.55±15(ms)传导时间短(P<0.01),提示随增龄血管弹性减低,阻力负荷增加,可作为心血管衰老生物标记之一;TSH虽随增龄有所提高,但性别间有差异,要排除影响因素也可作标记之一;Zn、Cu、IgA仅在男性组随年龄有改变,故尚不能作为敏感衰老生物标记。
In this paper, 31 healthy people including 31 cases of middle-aged and young group (20-40 years old), 31 cases of elderly (45-59 years old) and 39 cases of elderly (≥60 years old) were used as RP_1, RP_2, RP ), RP (μ-s), PEP, SOD, LPO, T_3, T_4, TSH, Zn, CuA, Ig, IgG and IgM. The results showed that the 1323 ± 149 (sigma U / gHb) of middle-aged and young group of SOD decreased to 1184 ± 103 (sigma U / gHb) with aging (P <0.01) The conduction time of RP (2-1) elderly group was 32.95 ± 13.53 (ms) was shorter than that of middle-aged group (44.55 ± 15 ms) (P <0.01), which suggested that the resistance load increased with aging, TSH, although increased with age, but there are differences between the sexes, to exclude the influencing factors can also be used as a marker; Zn, Cu, IgA only in men with age change, it can not be as sensitive Aging biomarkers.