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(一)应用成年雄性大鼠,体重在150～350克之间。药物为中国医学科学院药物研究所制的醋酸棉酚,以吐温80(Twecn 80)溶化后,加蒸馏水稀释,用自制钝头注射器喂灌。剂量为30毫克/日/公斤。(二)喂药2周后,垂体前叶促卵泡激素细胞体积轻度胀大,颗粒减少,促黄体素细胞无甚变化。3～4周后。促卵泡激素细胞,体积胀大显著,数目亦增多,胞浆内颗
(A) Apply adult male rats weighing between 150 and 350 grams. The drug was Gossypol acetic acid made by the Institute of Medicinal Science of the Chinese Academy of Medical Sciences. After being dissolved in Tween 80, it was diluted with distilled water and fed with a self-made blunt-head syringe. The dose is 30 mg/day/kg. (B) Two weeks after the administration of the drug, the volume of follicle stimulating hormone in the anterior pituitary gland swelled slightly, the number of particles decreased, and the number of luteinizing cells did not change. 3 to 4 weeks later. Follicle-stimulating hormone cells, the volume swelled significantly, the number also increased, the cytoplasm