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对正常患者、Ⅱ型糖尿病患者、糖耐量异常者和糖耐量正常但伴有高血压和/或高血脂者同时作胰岛素和胰高糖素释放试验,结果表明,糖尿病组胰岛素释放延迟,曲线低平而胰高糖素释放曲线峰值前移,各时相点虽比正常组相应点偏高,但无显著性差异(P>0.05),糖耐量异常组胰岛素释放曲线和胰高糖素释放曲线的变化与Ⅱ型糖尿病组相似,高血压/高血脂组胰岛素、胰高糖素及血糖与正常对照组无显著差异,提出将血糖、血浆胰岛素和胰高糖素3项指标综合分析,可为糖尿病早期诊断提供一个较敏感的指标.
In normal patients, patients with type 2 diabetes, impaired glucose tolerance, and those with normal glucose tolerance but with hypertension and / or hyperlipidemia, both insulin and glucagon release tests showed that insulin release was delayed and the curve was low in diabetic patients The peak of glucagon release was peaked and the peak of glucagon release curve was higher than that of the normal group at each time point, but no significant difference was found (P> 0.05). The insulin release curve and glucagon release curve The changes of insulin resistance, glucagon and glucose in hypertension / hyperlipidemia group were not significantly different from those in normal control group. The three indicators of blood glucose, plasma insulin and glucagon were analyzed comprehensively Early diagnosis of diabetes provides a more sensitive indicator.