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患者男,27岁。躯干、四肢反复发生暗红色丘疹、结节、坏死、结痂4月余,无痛,偶有瘙痒。皮肤科情况:躯干、臀部及四肢暗红色丘疹、结节,部分中央坏死、破溃,结黑褐色厚痂,留有萎缩性瘢痕或色素沉着。皮损组织病理示:真皮结节状淋巴及大组织样细胞浸润,可见多数异型细胞,约占30%,少数细胞呈双核或多核;免疫组化染色示:CD3(+),CD4(+),CD30(+),CD68(+),CD8个别(+),CD20个别(+),Ki-67约10%(+)。诊断:淋巴瘤样丘疹病。
Patient male, 27 years old. Trunk, repeated dark red papules, nodules, necrosis, scabs more than 4 months, painless, occasional itching. Dermatology: trunk, buttocks and limbs dark red papules, nodules, part of the central necrosis, ulceration, knot dark brown thick scab, leaving atrophic scar or pigmentation. The histopathology showed that the infiltration of dermal nodular lymphoid tissue and large tissue-like cells showed that most of the dysplastic cells, accounting for 30%, showed a few nuclei or multiple nuclei. Immunohistochemical staining showed that CD3 (+), CD4 (+) , CD30 (+), CD68 (+), CD8 individual (+), CD20 individual (+), Ki-67 approximately 10% (+). Diagnosis: lymphoid papulosis.