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目的:探讨经子宫动脉途径介入治疗CSP的可行性和临床疗效。方法:我院自2009年至今采用介入方法治疗22例子宫切口妊娠患者。经双侧子宫动脉超选择性插管,再经动脉导管行超选择性子宫动脉内灌注甲氨蝶呤(MTX)50-100mg,最后以明胶海绵颗粒栓塞子宫动脉。结果:22例患者介入手术均成功,2~3天内在B超引导下行清宫术,术中未见大量出血;患者术后均有下腹部疼痛,3例出现骶尾部疼痛,在经对症处理后均缓解。术后监测血HCG术后3日血β-HCG值降幅均超过50%,证明治疗有效。随访4年,22例患者术后平均7个月恢复规律月经,4例患者再次怀孕。结论:经子宫动脉途径介入治疗子子宫切口妊娠疗效较显著、成功率高,并可预防和控制破裂大出血,可避免切除子宫,并保留生育功能。
Objective: To investigate the feasibility and clinical efficacy of interventional therapy of CSP via uterine artery. Methods: Since 2009, 22 cases of uterine incision pregnancy have been treated by interventional method in our hospital. Transperfused bilateral uterine artery cannulation, and then through the arterial catheter line superselective uterine artery perfusion methotrexate (MTX) 50-100mg, and finally with gelatin sponge particles embolization of the uterine artery. Results: Twenty-two patients were successfully involved in the interventional procedure. Within 2 to 3 days, the curettage was performed under B-mode ultrasonography. There was no massive bleeding during the operation. All patients had lower abdominal pain and 3 cases of sacrococcygeal pain after operation. After symptomatic treatment Are ease. Postoperative blood HCG 3 days after blood β-HCG decreased by more than 50%, proving that the treatment is effective. After 4 years of follow-up, 22 patients recovered menstrual cycle after an average of 7 months and 4 patients became pregnant again. Conclusion: Interventional uterine artery intervention for the treatment of uterine incision pregnancy more effective, high success rate, and can prevent and control bleeding rupture, to avoid the removal of the uterus, and retain reproductive function.