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我们从1979年起使用国产硝苯吡啶口服胶丸(上海第十七制药厂和上海延安制药厂产品)治疗高血压病,现将50例原发性高血压患者的临床降压疗效和部分患者血液动力学变化报道如下。方法50例中,男37例,女13例。年龄30～67岁,平均49.2岁。高血压分期:Ⅰ期6例、Ⅱ期38例、Ⅲ期6例。根据治疗前舒张压高度,属轻型者(≤105毫米汞柱)11例、中型(106～125毫米汞柱)36例、重型(>125毫米汞柱)3例。大多数患者以往长期服用各种降压药,但疗效甚差或无效。治疗前停服其他降压药2周。2周后舒张压≥95毫米汞柱者,口服硝苯吡啶胶丸(5毫克/丸),剂
We have been using homemade nifedipine oral capsules (Shanghai No. 17 Pharmaceutical Factory and Shanghai Yan’an Pharmaceutical Factory) for the treatment of hypertension since 1979, and now 50 patients with essential hypertension clinical antihypertensive efficacy and some patients Hemodynamic changes are reported below. Methods 50 cases, 37 males and 13 females. Age 30 to 67 years, mean 49.2 years old. Hypertension staging: 6 cases of stage Ⅰ, 38 cases of stage Ⅱ, 6 cases of stage Ⅲ. According to the pre-treatment diastolic blood pressure, 11 were light (≤105 mmHg), 36 were medium (106-125 mmHg), and 3 were heavy (> 125 mmHg). Most patients in the past long-term use of a variety of antihypertensive drugs, but the effect is poor or ineffective. Stop taking other antihypertensive drugs for 2 weeks before treatment. 2 weeks after diastolic blood pressure ≥ 95 mm Hg, oral nifedipine capsules (5 mg / pill), the agent