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目的探讨呼吸科重症加强治疗病房院内肺部真菌感染患者临床特征,为日后诊断治疗提供理论依据。方法 33例呼吸科重症加强治疗病房院内肺部真菌感染患者作观察组,同期选择普通病房院内肺部真菌感染患者32例作为参考组,对比两组患者临床资料。结果观察组治疗有效率为36.36%,治疗无效率为48.48%,死亡率为15.15%;参考组治疗有效率为56.25%,治疗无效率为40.63%,死亡率为3.13%;观察组曲霉菌、光滑念珠菌和热带念珠菌感染率高于参考组,观察组平均住院时间为(48.14±11.06)d长于参考组的(28.48±7.19)d,两组治疗效果、病原菌分布情况和住院时间比较差异均有统计学意义(P<0.05)。结论呼吸科重症加强治疗病房院内肺部真菌感染发病率、死亡率均比较高,主要菌株为热带念珠菌、曲霉菌和耐氟康唑光滑念珠菌,应予以重视。
Objective To investigate the clinical features of patients with pulmonary fungal infection in intensive care unit of respiratory department and provide a theoretical basis for future diagnosis and treatment. Methods Thirty-three patients with pulmonary fungal infection in intensive care department of respiratory department were selected as the observation group. 32 patients with pulmonary fungal infection in the common ward were selected as the reference group in the same period, and the clinical data of two groups were compared. Results In the observation group, the effective rate was 36.36%, the treatment inefficiency was 48.48%, the mortality rate was 15.15%; the reference group was 56.25%, the treatment inefficiency was 40.63% and the mortality rate was 3.13% Candida and Candida tropicalis infection rate was higher than the reference group, the observation group average length of stay was (48.14 ± 11.06) d longer than the reference group (28.48 ± 7.19) d, the two groups were treated, the distribution of pathogens and hospital stay were compared There was statistical significance (P <0.05). Conclusions The incidence and mortality rate of lung fungal infections in intensive care unit of respiratory department are relatively high. The main strains are Candida tropicalis, Aspergillus fumigatus and Candida glabrata, which should be taken seriously.