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为了解ＨＬＡ第２类基因（ＨＬＡ－ＤＲ－ＤＱ，－ＤＰ位点）在中国人群中的分布情况，应用ＰＣＲ／ＳＳＯ方法对新疆的主要民族维吾尔族人９２例进行了ＨＬＡ－ＤＲＢ１、ＤＲＢ３、ＤＲＢ５和ＤＱＡ１、ＤＱＢ１五位点等位基因进行了分析，计算了它们在该人群中的分布频率，推导了ＤＲ－ＤＱ五位点单倍型的结构及分布。通过与世界各主要人种和中国北方汉族的比较，证明维族在中华民族有共同基因背景的基础上，还表现出与西方人种有一定程度的血缘交流。为研究古丝绸之路人口迁移对中国维族遗传特征的影响提供了资料。
To understand the distribution of HLA class 2 (HLA-DR-DQ, -DP) loci in Chinese population, PCR-SSO was used to detect HLA-DRB1, DRB3 and DRB5 in 92 ethnic Uygur nationalities in Xinjiang. And DQA1, DQB1 five-locus alleles were analyzed, calculated their frequency of distribution in the population, derived DR-DQ five-site haplotype structure and distribution. By comparing with the major ethnic groups in the world and the Han people in northern China, it is proved that Uyghur people have some degree of blood-related exchanges with Western ethnic groups on the basis of the common genetic background of the Chinese nation. Provided information for studying the impact of the migration of the ancient Silk Road on the genetic characteristics of Chinese Uighurs.