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1例66岁女性患者因骨折连续口服骨康胶囊和接骨七厘丸11 d，停药后第6天出现乏力、纳差、尿黄，再次服用上述两药并加服洛芬待因片5 d后症状加重，实验室检查示丙氨酸转氨酶（ALT）778 U/L，天冬氨酸转氨酶（AST）782 U/L，碱性磷酸酶（ALP）151 U/L，总胆红素（TBil）34.3 μmol/L，直接胆红素（DBil）24.0 μmol/L，γ-谷氨酰转移酶（γ-GT）111 U/L。考虑为骨康胶囊、接骨七厘丸和洛芬待因片导致的肝损伤。停用上述药物，予保肝、退黄治疗。21 d后复查，ALT 24 U/L，AST 17 U/L，ALP 104 U/L，TBil 13.6 μmol/L，DBil 9.0 μmol/L，γ-GT 52 U/L。“,”A 66-year-old female patient received n Gukang capsules and n Jieguqili pills orally for 11 days for fracture. On day 6 after the drugs withdrawal, she developed weakness, anorexia, and yellow urine. Drugs above-mentioned were re-given and ibuprofen and codeine phosphate tablets were added. Five days later, her symptoms were aggravated. Laboratory tests showed alanine aminotransferase (ALT) 778 U/L, aspartate aminotransferase (AST) 782 U/L, alkaline phosphatase (ALP) 151 U/L, total bilirubin (TBil) 34.3 μmol/L, direct bilirubin (DBil) 24.0 μmol/L, and gamma-glutamyltransferase (γ-GT) 111 U/L. It was considered to be liver injury caused by n Gukang capsules, n Jieguqili pills, and ibuprofen and codeine phosphate tablets. All drugs above were withdrawn and the liver-protective and anti-jaundice treatments were given. After 21 days, laboratory tests showed ALT 24 U/L, AST 17 U/L, ALP 104 U/L, TBil 13.6 μmol/L, DBil 9.0 μmol/L, and γ-GT 52 U/L.n