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线粒体是真核细胞中重要和独特的细胞器 ,在细胞凋亡和坏死过程中都发挥着关键作用。对心肌缺血再灌注 (ischemia reperfusion ,I/R)损伤机制的研究也表明 ,线粒体的功能损害是导致I/R心肌不可逆损伤的重要原因之一。本文综述了线粒体及线粒体KATP通道在缺血心肌保护方面的重要意义
Mitochondria are important and unique organelles in eukaryotic cells that play a key role in apoptosis and necrosis. Studies on the mechanism of myocardial ischemia-reperfusion (I / R) injury also indicate that the functional impairment of mitochondria is one of the important causes of irreversible damage to I / R myocardium. This article reviews the importance of mitochondrial and mitochondrial KATP channels in the protection of ischemic myocardium