论文部分内容阅读
[Objective]To investigate the effects of total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds on the cardiogram and hemodynamics of myocardial ischemia reperfusion(MIR) rats.[Method] Fifty SD rats were divided into 5 groups(sham operation group,model group,XD group,XZ group and XG group) randomly.Myocardial ischemia reperfusion injury model was induced by ligaturing the left anterior descending(LAD) of coronary artery for 30 min,and the changes of electrocardiogram before ligation,30 min after ligation,and 30,60 and 90 min after reperfusion were detected and recorded.In the end,LVSP,LVDEP,±dp/dtmax and HR were detected.[Result] Compared with the rats in model group,the height of J point of myocardial ischemia reperfusion rat treated with total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds descended,and the injury level of LVSP,LVDEP,±dp/dtmax and HR relieved.[Conclusion] Total polyphenols extracted from Toona sinensis(A.Juss.) Roem.seeds played a protective role in myocardial ischemia reperfusion induced injury.
[Objective] To investigate the effects of total polyphenols extracted from Toona sinensis (A. Juss.) Roem. Seeds on the cardiogram and hemodynamics of myocardial ischemia reperfusion (MIR) rats. [Method] Fifty SD SD rats were divided into 5 groups operation group, model group, XD group, XZ group and XG group randomly.Myocardial ischemia reperfusion injury model was induced by ligaturing the left anterior descending (LAD) of coronary artery for 30 min, and the changes of electrocardiogram before ligation, 30 min after ligation, and 30, 60 and 90 min after reperfusion were detected and recorded. In the end, LVSP, LVDEP, ± dp / dtmax and HR were detected. [Result] Compared with rats in model group, the height of J point of myocardial ischemia reperfusion rat treated with total polyphenols extracted from Toona sinensis (A. Juss.) Roem. seeds descended, and the injury level of LVSP, LVDEP, ± dp / dtmax and HR relieved. (A.Juss.) Roem.seeds played a protec tive role in myocardial ischemia reperfusion induced injury.