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作者观察了枢复宁预防肿瘤化疗恶心呕吐反应的疗效，共３３例，其中３１例是接受含顺铂的联合化疗，男性２４例，女性７例，年龄３６岁～７２岁。采用两种止吐方案控制呕吐反应。一组是于使用顺铂前半小时静脉推注枢复宁８ｍｇ；另一组是胃复安２０ｍｇ肌注加安定１０ｍｇ（或非那根２５ｍｇ）肌注，于使用顺铂前半小时用。结果３１例用枢复宁控制恶心的有效率为８０．６％，控制呕吐的有效率为９３．５％。２０例用胃复安对照组者各为３０．０％和３５．０％，两组有显著差异。枢复宁预防顺铂引起的恶心呕吐反应效果优于胃复安，副作用小，是一种比较理想的化疗止吐药物。
The authors observed the efficacy of shufuingning in the prevention of nausea and vomiting response to chemotherapy for cancers. A total of 33 patients were involved, 31 of whom received combination chemotherapy with cisplatin. There were 24 males and 7 females, aged 36 to 72 years. Two antiemetics were used to control emesis. One group was given an intravenous infusion of shufuning 8mg half an hour before using cisplatin; the other group was intramuscular injection of metoclopramide 20mg intramuscularly plus diazepam 10mg (or phenagen 25mg), which was used half an hour before cisplatin was used. Results The effective rate of control of nausea in 31 cases was 80.6% and that of vomiting was 93.5%. In the 20 cases with the metoprolol control group, 30.0% and 35.0% respectively, and there were significant differences between the two groups. The efficacy of shufuning in preventing nausea and vomiting caused by cisplatin is superior to metoclopramide, with less side effects, and is an ideal antiemetic drug for chemotherapy.