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目的:分析老年阿尔茨海默症患者治疗期间采用多学科协作护理的应用效果。方法:选取广东三九脑科医院2019年4月至2020年4月收治的老年阿尔茨海默症患者88例，随机数字表法分为对照组和观察组，各44例。观察组中男27例，女17例，年龄（68.18±5.19）岁，病程（3.92±0.73）年，采用多学科协作护理；对照组中男29例，女15例，年龄（67.43±5.06）岁，病程（3.86±0.78）年，采用常规护理。采用简易精神状态评价量表（MMSE）、巴氏指数量表（BI）、健康调查简表（SF-36）、阿尔茨海默病认知功能评定表（ADAS-cog）、蒙特利尔认知评估量表（MoCA）比较两组患者护理前、护理3个月后的精神状态、生活质量、认知功能情况，比较两组患者的不良事件、满意度情况。结果:观察组患者护理3个月后的MMSE评分为（23.64±3.17）分，高于对照组的（19.72±3.26）分，差异有统计学意义（n P＜0.05）；观察组患者护理3个月后的BI评分为（76.61±4.03）分、SF-36评分为（75.46±3.67）分、MoCA评分为（24.34±2.86）分、护理满意度为（91.26±2.59）%，均高于对照组［分别为（71.37±3.71）分、（71.08±4.16）分、（20.21±2.77）分、（85.68±3.27）%］，差异均有统计学意义（均n P＜0.05）；观察组患者护理3个月后ADAS-cog评分为（38.25±3.03）分、不良事件发生率为2.27%（1/44），均低于对照组［分别为（42.18±2.82）分、18.18%（8/44）］，差异均有统计学意义（均n P＜0.05）。n 结论:对于老年阿尔茨海默症患者来说，临床治疗期间采用多学科协作护理措施，能够有效改善患者的精神状态和认知功能，从而提高患者生活质量，降低患者不良事件的发生率，在临床应用效果显著，可在临床推广应用。“,”Objective:To analyze the effect applying multidisciplinary collaborative nursing during treatment for elderly patients with Alzheimer\'s disease.Methods:Eighty-eight elderly patients with Alzheimer\'s disease treated at Guangdong Sanjiu Brain Hospital from April 2019 to April 2020 were selected, and were divided into a control group and an observation group by the random number table method, with 44 cases in each group. The observation group had 27 males and 17 females and were given multidisciplinary collaborative nursing, with an age of (68.18±5.19) and a disease course of (3.92±0.73) years. The control group had 29 males and 15 females and were given routine nursing, with an age of (67.43±5.06) and a disease course of (3.86±0.78) years. The mental states, quality of life, and cognitive function of the two groups before and 3 months after the nursing were evaluated by Mini Mental State Examination (MMSE), Barthel Index (BI), Short Form of 36 Health Survey Qestionnaire (SF-36), Alzheimer \'s Disease Assessment Scale-cognitive (ADAS-cog), and Montreal Cognitive Assessment (MoCA) and were compared. The incidences of adverse events and nursing satisfaction were compared between these two groups.Results:The scores of MMSE, BI, SF-36, and MoCA 3 months after the nursing and the satisfaction in the observation group were higher than those in the control group [(23.64±3.17) vs. (19.72±3.26), (76.61±4.03) vs. (71.37±3.71), (75.46±3.67) vs. (71.08±4.16), (24.34±2.86) vs. (20.21±2.77), and (91.26±2.59)% vs. (85.68±3.27)%], with statistical differences (all n P＜0.05). Three months after the nursing, the score of ADAS-cog and the incidence of adverse events in the observation group were lower than those in the control group [(38.25±3.03) vs. (42.18±2.82) and 2.27% (1/44) vs. 18.18% (8/44)], with statistical differences (bothn P＜0.05).n Conclusions:For elderly patients with Alzheimer\'s disease, the use of multidisciplinary collaborative nursing measures during clinical treatment can effectively improve their mental state, cognitive function, and quality of life, and reduce the incidence of adverse events. The clinical application effect is remarkable, and it can be promoted and applied in clinical practice.