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目的：综述右旋酮洛芬立体选择性药动学和药效学性质。方法：从药动学、抗炎、镇痛及胃肠道毒副作用等几个方面介绍。结果：ｐｏ１２．５ｍｇ或２５ｍｇ右旋酮洛芬氨丁三醇与ｐｏ２５ｍｇ或５０ｍｇ的酮洛芬的相对生物活性是相同的，右旋酮洛芬氨丁三醇能迅速吸收，Ｔｍａｘ为０．２５～０．７５ｈ，而酮洛芬的Ｔｍａｘ为０．５～３ｈ，右旋酮洛芬的抗炎镇痛作用与２倍量的酮洛芬相同，左旋体的活性很低。结论：酮洛芬的抗炎镇痛作用是右旋体导致的，左旋体几乎无活性
Objective: To summarize the stereoselective pharmacokinetics and pharmacodynamic properties of dexketoprofen. Methods: From pharmacokinetics, anti-inflammatory, analgesic and gastrointestinal side effects and other aspects introduced. Results: The relative bioavailability of pox 2.5 mg or 25 mg of dexketoprofen trometamol with po25 mg or 50 mg of ketoprofen is comparable with that of dexketoprofen trometamol with a Tmax of 0.25 ~ 0.75h, and ketoprofen Tmax 0.5 ~ 3h, dexketoprofen anti-inflammatory analgesic effect and 2 times the amount of ketoprofen the same, low activity of levorotans. Conclusion: The antiinflammatory and analgesic effect of ketoprofen is caused by dextran, and the activity of levomyoma is almost no