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目的观察调强适形放射治疗(IMRT)结合热疗治疗颈部转移性肿瘤的治疗效果。方法将选取的111例颈部转移肿瘤患者随机分为观察组(56例)和对照组(55例)。对照组患者采用IMRT,观察组患者采用IMRT+热疗,比较两组患者的临床疗效。结果观察组患者鼻咽癌、食管癌、肺癌、口腔癌和喉癌的颈部转移癌的有效率分别为91.7%、87.5%、83.3%、100.0%和80.0%,对照组患者分别为45.5%、28.6%、28.6%、33.3%和33.3%,差异有统计学意义(P<0.05)。结论调强适形放射治疗结合热疗治疗颈部转移肿瘤疗效好,对无法切除的颈部转移肿瘤是一种较好的治疗手段。
Objective To observe the effect of IMRT combined with hyperthermia in the treatment of cervical metastatic tumors. Methods 111 patients with neck metastasis were randomly divided into observation group (56 cases) and control group (55 cases). Control group patients using IMRT, observation group patients using IMRT + hyperthermia, the clinical efficacy of two groups were compared. Results The effective rates of cervical metastasis of nasopharyngeal carcinoma, esophageal carcinoma, lung cancer, oral cavity cancer and laryngeal cancer in the observation group were 91.7%, 87.5%, 83.3%, 100.0% and 80.0% respectively, while those in the control group were 45.5% , 28.6%, 28.6%, 33.3% and 33.3%, respectively. The difference was statistically significant (P <0.05). CONCLUSION: Intensity-modulated conformal radiotherapy combined with hyperthermia in the treatment of neck metastases has good curative effect and is a good treatment for unresectable cervical metastases.