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目的 居室氡暴露是导致肺癌死亡的第二位重要原因,这是地下矿工氧暴露研究的外推结果。本分析就是为了验证此预测的正确性。方法 中国进行的两项居室氡暴露肺癌病例-对照研究共包括1050肺癌病例和1996名对照,把这些数据汇总在一起进行分析。结果 根据线性模型,在95％置信区间情况下,每100Bq/m~3的附加比值比(EOR)为0.133(0.01,0.036)。对在现住所居住30a以上的调查对象进行分析,EOR值为0.315(0.07,0.91)。此估算值与矿工数据外推值及北美和欧洲室内氡研究结果类似。结论 在众多居室中普遍存在的氡浓度长期暴露,会使肺癌危险度增加。
The purpose of indoor radon exposure is the second leading cause of lung cancer death, which is the extrapolation of the study of the underground miners’ oxygen exposure. This analysis is to verify the correctness of this prediction. METHODS: Two cases of lung cancer exposed to radon in China were included in the control study. A total of 1050 cases of lung cancer and 1996 controls were included in the control study. The data were collected for analysis. Results According to the linear model, the additional odds ratio (EOR) per 100Bq / m ~ 3 was 0.133 (0.01, 0.036) at a 95% confidence interval. Analysis of respondents living in current residences for more than 30 years showed EOR values of 0.315 (0.07, 0.91). This estimate is similar to the miner data extrapolation values and the results of indoor radon studies in North America and Europe. Conclusion Long-term exposure to radon concentrations, which are prevalent in many living rooms, can increase the risk of lung cancer.