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目的 为了解血液病致死性医院感染及相关危险因素。方法 回顾分析了 5年来我院血液病住院患者 5 10例有关临床资料。结果 医院感染率为 17.0 5 % ,其中 2 8.7%死亡。在医院感染死亡患者中 ,中性粒细胞 ( PMN)、CD4及 CD8比例显著下降。感染的病原菌以革兰阴性杆菌及念珠菌为主 ,并以下呼吸道及血液感染多见。结论 人体免疫功能极度低下是导致感染死亡的主要内在因素 ,对该类患者应加强防护。
Objective To understand the fatal nosocomial infection of blood diseases and related risk factors. Methods A retrospective analysis of 5 hospitalized patients with blood diseases in our hospital 5 10 cases of clinical data. Results The rate of nosocomial infection was 17.0 5%, of which 28.7% were fatal. In nosocomial death patients, neutrophil (PMN), CD4 and CD8 ratio decreased significantly. Infected pathogens to Gram-negative bacilli and Candida-based, and more common respiratory and bloodstream infections. Conclusion The extremely low immune function of human beings is the main internal factor leading to the death of infection, and the protection should be strengthened for these patients.