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目的探讨干扰素联合思密达治疗轮状病毒性肠炎的临床效果。方法将我院收治的100例轮状病毒性肠炎的患儿,随机分为对照组和观察组,每组各50例,在常规治疗的基础上对照组采用思密达治疗,观察组在对照组的基础上加用干扰素治疗,比较两组的治疗效果和不良反应发生情况。结果观察组总有效率96%,对照组总有效率80%。观察组总有效率明显优于对照组,差异有统计学意义(χ2=5.82,P<0.05)。两组治疗过程中,均未见明显不良反应发生。结论干扰素联合思密达治疗小儿腹泻疗效好,副作用少,使用方便,值得临床推广应用。
Objective To investigate the clinical effect of interferon combined with Smecta in the treatment of rotavirus enteritis. Methods 100 cases of rotavirus enteritis admitted to our hospital were randomly divided into control group and observation group, 50 cases in each group. On the basis of conventional treatment, the control group was treated with Smecta, while in the control group, Group based on the addition of interferon treatment, the treatment effect and adverse reactions were compared between the two groups. Results The total effective rate was 96% in observation group and 80% in control group. The total effective rate in the observation group was significantly better than that in the control group, with significant difference (χ2 = 5.82, P <0.05). Two groups of treatment, no significant adverse reactions occurred. Conclusion Interferon combined with Smectite treatment of children with diarrhea, less side effects, easy to use, worthy of clinical application.