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目的:研究中药复方联合更昔洛韦治疗婴儿巨细胞病毒性肝炎的临床疗效。方法:按随机分组法将60名巨细胞病毒性肝炎患儿分为2组,对照组30例,治疗组30例。2组均使用更昔洛韦治疗。治疗组在此基础上加用中药复方治疗。4周后复查血清TBIL、ALT、AST、TBA、γ-GT,观察肝脾回缩情况,并将2组患儿住院时间进行比较。结果:治疗4周后,治疗组血清TBIL、ALT、AST、TBA明显下降,γ-GT明显升高,与对照组比较有显著差异(P<0.05或P<0.01)。治疗组肝脾回缩情况明显优于对照组。治疗组住院时间明显短于对照组。结论:更昔洛韦联合中药复方治疗婴儿巨细胞病毒性肝炎疗效好,住院时间短。
Objective: To study the curative effect of traditional Chinese medicine combined with ganciclovir in the treatment of infant cytomegalovirus hepatitis. Methods: Sixty children with cytomegalovirus were randomly divided into two groups according to the randomization method: control group (30 cases) and treatment group (30 cases). Both groups were treated with ganciclovir. On the basis of this, the treatment group added traditional Chinese medicine compound therapy. After 4 weeks, the serum TBIL, ALT, AST, TBA and γ-GT were reexamined, and the contraction of liver and spleen was observed. The hospitalization time of two groups were compared. Results: The serum levels of TBIL, ALT, AST and TBA were significantly decreased and γ-GT were significantly increased in the treatment group after 4 weeks of treatment, which were significantly different from those in the control group (P <0.05 or P <0.01). Treatment group liver and spleen contraction was significantly better than the control group. Treatment group was significantly shorter hospital stay than the control group. Conclusion: Ganciclovir combined with traditional Chinese medicine in the treatment of infant cytomegalovirus has good efficacy and short hospital stay.