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近年来曾见到因用乙亚胺类药物治疗银屑病引起白血病的病例报告,现将我们见到的一例报告如下。患者男,35岁,电工。因头昏乏力、齿龈肿胀、发烧2mo,于1988—01—02入院。因患银屑病,1983年起服用乙亚胺治疗,5yr期间曾间断口服6瓶,共约600片(60g)。于入院前2mo自觉头昏、乏力,并逐渐加重。牙龈肿胀、疼痛、不能进食、发烧、皮肤出血、便血来院诊治。体检:体温39℃、脉搏130次/min、呼吸22次/min、血压17.33/10.67kpa。贫血外观、皮肤可见散在出血点、躯干部皮肤色素丢失呈斑块分布(银屑病缓解的皮肤改变),巩膜无黄染、牙银肿胀、全口牙齿松动明显、张口困难。
In recent years, we have seen cases of leukemia caused by acetaminophen in the treatment of psoriasis. We report the following case report. Male patient, 35 years old, electrician. Due to dizziness, swollen gums, fever 2mo, admitted to the hospital in January 1988. Due to psoriasis, taking acetaminophen from 1983 onwards, intermittent 6 bottles during 5yr, a total of about 600 (60g). 2mo before admission, consciously dizziness, fatigue, and gradually increased. Gingival swelling, pain, can not eat, fever, skin bleeding, blood in the hospital for treatment. Physical examination: body temperature 39 ℃, pulse 130 beats / min, breathing 22 times / min, blood pressure 17.33 / 10.67kpa. Anemia appearance, scattered bleeding spots in the skin, skin pigmentation of the trunk area was patchy (psoriasis alleviate the skin changes), scleral no yellow dye, tooth silver swelling, full mouth loose teeth, mouth opening difficulties.