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二尖瓣脱垂(以下简称PMV)近年来渐受注意,可引起心律不齐,二尖瓣闭锁不全,细菌性心内膜炎甚至死亡。心脏超声波研究在“正常”青年中其发病率为男0.5%,女6%。本文报告12例经过心脏血管造影证实PMV患者伴有反复一过性脑缺血性发作或不完全非进行性卒中。这些病例是探索试用血小板抑制药物治疗一过性脑缺血发作(简称T1A)及不完全非进行性卒中时发现的。其中男7人,女5人,年龄自18~67岁,平均38岁。而另一组有动脉硬化的T1A发作患者平均年龄是62岁。12例PMV患者的心脏症状大多为胸痛,心悸,头晕,晕厥,面色苍白等。体检有收缩中期喀喇音或收缩中期,后期或全期的杂音,窦性心动过速,结性期外,阵发性房颤等。一例有室性心动过速,在二年后死亡。另一例有心室内传导阻滞。亦有无症状及体征者。神经系统表现:8例有多次发作,4例为单次发作。间歇期为数月或数年,或更短。较多的是典型的T1A,
Mitral valve prolapse (hereinafter referred to as PMV) more and more attention in recent years, can cause arrhythmia, mitral regurgitation, bacterial endocarditis and even death. Cardiac ultrasound studies show a prevalence of 0.5% for males and 6% for females in “normal” youth. This article reports 12 patients confirmed by cardiac angiography PMV patients with recurrent transient ischemic attack or incomplete non-progressive stroke. These cases were explored to explore the use of platelet-inhibiting drugs in the treatment of transient ischemic attacks (T1A) and incomplete non-progressive stroke found. Including 7 males and 5 females, aged 18 to 67 years old, an average of 38 years old. The mean age of patients with T1A episodes of arteriosclerosis in another group was 62 years. The cardiac symptoms of 12 patients with PMV were mostly chest pain, heart palpitations, dizziness, fainting, pale and so on. Physical examination has contracted the mid-term Kara tone or contraction mid-term, late or full-term murmur, sinus tachycardia, nodal period, paroxysmal atrial fibrillation. One case had ventricular tachycardia and died two years later. Another case of intraventricular conduction block. There are also symptoms and signs. Nervous system performance: 8 cases have multiple attacks, 4 cases of a single attack. Intermittent periods are months or years, or shorter. More is a typical T1A,