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作者用光化学疗法治疗73名蕈样肉芽肿患者,年龄16～80岁(平均58岁)。男∶女=1.4∶1。平均发病年龄47岁。诊断都经组织切片。患者的分期和病期见表Ⅰ。这些患者以往经过各种治疗包括激素、放射、电子束、紫外线(UVB)、细胞毒药物、氮芥等而没有效果。治疗方法为口服8-MOP 按0.6mg/kg 体重2小时后全身用长波紫外线(UVA)照射。大多致病人 UVA 初量为1.5或2.5焦耳(J)/cm~2,以后根
The authors treated 73 patients with mycosis fungoides with photochemotherapy and were 16 to 80 years old (mean 58 years old). Male: female = 1.4:1. The average age of onset is 47 years. The diagnosis has been tissue sectioned. The stage and stage of the patient are shown in Table I. These patients have not been effective in the past through various treatments including hormones, radiation, electron beam, ultraviolet (UVB), cytotoxic drugs, nitrogen mustard, and the like. The treatment was oral UV-irradiation (UVA) after oral administration of 8-MOP at 0.6 mg/kg body weight for 2 hours. Most of the patient’s initial UVA dose is 1.5 or 2.5 joules (J)/cm~2.