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的了解扩张后皮肤慢性损害的动态修复过程。方法选用７ｋｇ左右的狗为实验动物。实验分为扩张后即时、１个月、３个月、６个月、１年及对照组共６组，采用超微结构的观察及胶原定量分析等研究手段。结果发现扩张刺激可致皮肤慢性损害，早期修复表现为成纤维细胞功能活跃，胶原合成增加；随着时间的延长，成纤维细胞结构渐趋稳定，密体、密斑消失，胞浆减少，微粒纤细；大部分胶原纤维恢复正常的网状结构，但部分胶原纤维排列紊乱，呈“漩涡状”排列，似“瘢痕样”改变。结论扩张可致皮肤慢性损害，扩张后真皮组织修复并非组织再生
Understand the dynamic repair process of chronic damage to the skin after expansion. Methods 7kg or so dogs were selected as experimental animals. The experiment was divided into 6 groups: immediate expansion, 1 month, 3 months, 6 months, 1 year and control group, using ultrastructural observation and collagen quantitative analysis. The results showed that the expansion stimulation can cause chronic skin damage, early repair manifested as active fibroblasts, collagen synthesis increased; as time goes by, the fibroblast structure gradually stabilized dense body, dense spots disappear, reduced cytoplasm, particles Slender; most of the collagen fibers to restore the normal network structure, but some collagen fibers arranged in disorder, was “swirling” arrangement, like “scar-like” change. Conclusions Expansion can cause chronic skin damage, dermal tissue expansion after dilation is not tissue regeneration