在广西梧州市对20,726人进行EB病毒IgA/VCA抗体血清学普查和4年追踪观察,共发现35例鼻咽癌病人,其中早期病人占91.5％。同期门诊查出的1,036例鼻咽癌中,早期病人仅占31.8％。在鼻咽癌确诊前16～41个月即可检出IgA/VCA抗体。说明EB病毒与鼻咽癌的发生关系密切,血清学普查和追踪观察对本病的早期诊断十分重要。 A total of 20,726 persons were screened for EB virus IgA/VCA antibody serology in Zhuozhou, Guangxi, and 4 years of follow-up observation. A total of 35 cases of nasopharyngeal carcinoma were found, of which 91.5% were early patients. Of the 1,036 nasopharyngeal carcinomas detected during outpatient consultations, 31.8% were early patients. The IgA/VCA antibodies can be detected 16 to 41 months before the diagnosis of nasopharyngeal carcinoma. Epstein-Barr virus is closely related to the occurrence of nasopharyngeal carcinoma, serological survey and follow-up observation is very important for the early diagnosis of this disease.