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目的探讨妊娠瘙痒性荨麻疹性丘疹和斑块的临床表现及其对新生儿的影响。方法选择妊娠瘙痒性荨麻疹性丘疹和斑块患者50例作为观察组,同时选取同一时期的正常孕妇50作为对照组,观察观察组孕妇的临床表现,并比较两组孕妇血清IgA、IgM、IgG的水平及分娩新生儿体重与湿疹患病率。结果在孕28~36周间其发病率为72.0%,64.0%的患者皮疹范围除了腹部外,还包括大腿近端、胸部、背部等其他部位中一处,82.0%的患者出现中重度的瘙痒症状;观察组患者血清IgA、IgM、IgG水平与对照组相比差异无统计学意义(P>0.05);观察组新生儿体重为(3 587±621)g明显高于对照组(3 216±520)g,且观察组新生儿湿疹患病率38.0%明显高于对照组新生儿湿疹患病率22.0%,两组比较差异有统计学意义(P<0.05)。结论妊娠瘙痒性荨麻疹性丘疹和斑块主要会出现较为严重的瘙痒,皮疹范围出现在患者的腹部并累及躯干、臀部与大腿,会增加新生儿的体重与其湿疹的患病率。
Objective To investigate the clinical manifestations of pruritus urticaria and plaque in pregnancy and their effects on neonates. Methods Fifty patients with pruritic papular papules and plaques in pregnancy were selected as the observation group. Meanwhile, 50 normal pregnant women in the same period were selected as the control group. The clinical manifestations of the pregnant women in the observation group were observed. The serum IgA, IgM, IgG The level of newborn birth weight and eczema prevalence. Results The incidence rate was 72.0% between 28 and 36 weeks of pregnancy. In addition to the abdomen, 64.0% of the patients had rash, including one of the proximal thigh, chest, back and other parts. 82.0% of the patients had moderate to severe pruritus There was no significant difference in serum IgA, IgM and IgG levels between the observation group and the control group (P> 0.05). The body weight of neonates in the observation group was significantly higher than that of the control group (3 587 ± 621 g) 520) g, and the prevalence of neonatal eczema in the observation group was 38.0%, which was significantly higher than that of the control group (22.0%). The difference between the two groups was statistically significant (P <0.05). CONCLUSION Pruritus and papules in pregnancy are associated with severe pruritus. The rash area appears in the abdomen of the patient and affects the trunk, buttocks and thighs, increasing the weight of the newborn and the prevalence of eczema.