论文部分内容阅读
复发性口腔溃疡(ROU)的病因尚未完全确定,可能与免疫遗传学有关。近年来的研究显示,父母患有ROU者,其孩子中ROU的患病率也明显增加,从而提示ROU的易感性可能与HLA有关联。ROU与HLA-A_2,-B_(12),-Bw_(44)和β_2-微球蛋白的关联已有报告,但尚无定论。鉴于已有证明某些疾病与Ⅱ类基因关系密切。作者对华人ROU患者HLA-DR和HLA-DQ抗原进行了测定。共检测了80例ROU患者(男性36例,女性44例),年龄为19～64岁。并以无口腔粘膜疾患史的107名健康者作为对照组。对
The etiology of recurrent oral ulcer (ROU) has not yet been completely determined, and may be related to immune genetics. In recent years, studies have shown that parents with ROU, the prevalence of ROU in their children also increased significantly, suggesting that the susceptibility of ROU may be associated with HLA. The association of ROU with HLA-A_2, -B_ (12), -Bw_ (44) and β_2-microglobulin has been reported, but no conclusion has been reached yet. In view of the fact that some diseases have been proved to be closely related to type II genes, The authors tested HLA-DR and HLA-DQ antigens in Chinese ROU patients. A total of 80 patients with ROU were examined (36 males and 44 females) aged 19-64 years. 107 healthy people without a history of oral mucosal disease were selected as the control group. Correct