糖尿病性神经病变是糖尿病最常见的并发症之一,发病率可高达40%~90%,男女发病率相近,发病率随病程的延长而逐年上升,发病早期约为7.5%,25年内50%的糖尿病患者会出现神经病变的临床症状,如果考虑亚临床症状,发病率可高达90%,10%~18%的患者在糖尿病初诊时就存在神经传导异常。糖尿病性神经病变可损害躯体交感神经和副交感神经,无髓神经纤维和小的髓神经纤维较早地发生严重的变 Diabetic neuropathy is one of the most common complications of diabetes, the incidence rate can be as high as 40% to 90%, the incidence of male and female similar, the incidence increases with the duration of the disease increased year by year, the incidence of about 7.5%, 50% Of diabetic patients develop clinical symptoms of neuropathy. If subclinical symptoms are considered, the incidence may reach as high as 90%. In patients with diabetes, 10% to 18% of patients have abnormalities of nerve conduction. Diabetic neuropathy can damage the somatic sympathetic and parasympathetic, unmyelinated and small myelinated fibers earlier severe changes