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目的:评价果糖二磷酸钠(FDP)治疗室上性及室性期前收缩的疗效及安全性。方法:FDP组45例,除使用常规抗心律失常药物治疗外,加用FDP 5~10 g,静脉滴注,1次/d,7~14 d为1个疗程。另设对照组45例,仅用常规抗心律失常药物治疗,7~14 d为1个疗程。结果:FDP组总有效率88.89%,对照组62.22%,两组间有统计学差异(P<0.05)。FDP组临床使用中不良反应少且轻。结论:加用FDP治疗室上性及室性期前收缩安全有效。
Objective: To evaluate the efficacy and safety of fructose diphosphate (FDP) in the treatment of supraventricular and ventricular premature contractions. Methods: Forty-five patients in FDP group were treated with FDP 5 ~ 10 g intravenously, once daily and 7 ~ 14 days in addition to conventional antiarrhythmic drugs. Another control group of 45 cases, only with conventional anti-arrhythmic drugs, 7 to 14 days for a course of treatment. Results: The total effective rate was 88.89% in FDP group and 62.22% in control group, with statistical significance (P <0.05). Adverse reactions in the FDP group were less and lighter in clinical use. Conclusions: Addition of FDP is safe and effective for supraventricular and ventricular contractions.