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目的:观察短期胰岛素强化治疗初诊2型糖尿病的疗效。方法:将新诊断的2型糖尿病患者90例随机分为两组,观察组50例予胰岛素强化治疗,对照组40例给予口服降糖药物治疗,比较两组治疗前后空腹血糖(FPG)、餐后2 h血糖(2hPG)、糖化血红蛋白(HbA1c)、空腹胰岛素(FINS)、C2肽(C2P)。结果:治疗后2组的各项指标均较治疗前有所改善(P<0.05),且观察组FPG、2hPG、HbA1c下降指数较对照组明显,FINS、C2P升高指数较对照组明显,两组差异有统计学意义(P<0.05)。结论:初诊2型糖尿病患者予短期胰岛素强化治疗有利于改善血糖和胰岛功能。
Objective: To observe the effect of short-term intensive insulin treatment of newly diagnosed type 2 diabetes mellitus. Methods: 90 newly diagnosed type 2 diabetic patients were randomly divided into two groups. 50 cases in the observation group were treated with intensive insulin therapy and 40 cases in the control group were treated with oral hypoglycemic drugs. The fasting blood glucose (FPG) 2hPG, HbA1c, FINS and C2P after 2h. Results: After treatment, the indexes in both groups were improved compared with that before treatment (P <0.05), and the descending index of FPG, 2hPG and HbA1c in the observation group were significantly higher than those in the control group The difference was statistically significant (P <0.05). Conclusion: The newly diagnosed type 2 diabetic patients give short-term intensive insulin therapy is conducive to improving blood glucose and pancreatic islet function.