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Jean Berger于1968年首次报告系膜IgA肾病(IgAN)[1]。四十年来这一名词被全球广泛应用,无数的患者通过肾活检被冠以这一诊断。然而有关IgAN的发病机理特别是治疗方法的进展则很少,效果不佳。其根本原因在于IgAN不是一个独立的疾病。Berger当时对本病的诊断定义是非常含糊的,其
Jean Berger first reported mesangial IgA nephropathy (IgAN) in 1968 [1]. The term has been widely used in the world for 40 years and countless patients have been diagnosed with renal biopsy. However, the pathogenesis of IgAN, especially the progress of treatment are few, the effect is not good. The fundamental reason is that IgAN is not an independent disease. Berger’s definition of the diagnosis of the disease was very vague at the time