静脉注射西洋参茎叶提出的皂甙150mg/kg,可显著对抗氯化钡诱发的大鼠心律失常,可预防急性心肌缺血诱发的大鼠心律失常以及氯仿-肾上腺素引起的兔心律失常,并能增加豚鼠对哇巴因的耐量。腹腔注射,可预防氯仿诱发的小鼠室颤。在离体实验中,小剂量皂甙可增强豚鼠乳头肌的收缩性,大剂量则抑制其收缩性,延长不应期,明显降低自律性,而对兴奋性则无明显影响。 Intravenous injection of saponin (150mg/kg) from stems and leaves of American ginseng can significantly counteract the arrhythmia induced by lanthanum chloride in rats, and can prevent arrhythmias induced by acute myocardial ischemia in rats and arrhythmias induced by chloroform-adrenergic in rabbits. Increase the tolerance of guinea pigs to ouabain. Intraperitoneal injection can prevent chloroform-induced ventricular fibrillation in mice. In vitro experiments, low-dose saponins can enhance the contractility of guinea pig papillary muscles, high doses inhibit its contractility, extended refractory period, significantly reduced self-discipline, but no significant effect on excitability.