飞秒激光小切口角膜基质透镜取出术(SMILE)作为一种相对较新的角膜屈光手术方式,目前还处在不断探索的发展阶段.虽然临床研究显示出其具有较好的安全性、有效性、可预测性及稳定性,然而术后临床效果不尽相同,个体差异较大.如何通过设定个性化的手术参数以实现更好的视觉质量是目前研究的焦点问题之一,需要在临床上不断地进行摸索,并给予优化和必要的调整.本文就SMILE中手术设计,如脉冲能量、扫描模式、角膜帽、手术切口、光学区对手术效果的影响予以综述.“,”As a relatively new procedure,small incision lenticule extraction (SMILE) is still in its initial stage.Despite the fact that it has shown safety,efficacy,predictability,and stability,the clinical outcomes were diversiform among individuals.How to improve visual quality by designing individualized parameters is one of the researching focuses in corneal refractive surgery.This article reviewed the operative design,such as pluse energy,scanning patterns,cap,incision,optical zone and its influences on surgical results.