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目的:探讨复方甘草酸苷联合还原性谷胱甘肽治疗药物性肝损害(DILI)的疗效。方法:将70例DILI患者分为治疗组35例和对照组35例,治疗组加用复方甘草酸苷和还原性谷胱甘肽治疗。结果:治疗组治疗后患者血清ALT、AST、TBIL、AKP下降明显,与对照组治疗后比较有显著性差异。结论:复方甘草酸苷联合还原性谷胱甘肽治疗DILI,效果显著,具有临床应用价值。
Objective: To investigate the efficacy of compound glycyrrhizin combined with reduced glutathione in the treatment of drug-induced liver damage (DILI). Methods: Seventy patients with DILI were divided into treatment group (35 cases) and control group (35 cases). The treatment group was treated with compound glycyrrhizin and glutathione. Results: After treatment, the serum ALT, AST, TBIL and AKP in the treatment group decreased significantly compared with the control group after treatment. Conclusion: Compound glycyrrhizin combined with reduced glutathione in the treatment of DILI, the effect is significant, with clinical value.