论文部分内容阅读
肝星状细胞活化增殖是肝纤维化发生的关键。肝星状细胞在活化增殖过程中受多种细胞因子或蛋白的调控,通过表面受体激活信号转导网络系统,促使肝纤维化的发生发展。这些表面受体和信号转导通路成为研究的靶向,为纤维化的发生和逆转提供理论依据。
Hepatic stellate cell activation and proliferation of liver fibrosis is the key. Hepatic stellate cells in the process of activation and proliferation by a variety of cytokines or proteins in the regulation, through the surface receptor activation signal transduction network system, prompting the development of liver fibrosis. These surface receptors and signal transduction pathways become the target of study, providing a theoretical basis for the occurrence and reversal of fibrosis.