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目的探讨急性脑梗死患者血清钙、镁离子、血糖浓度变化及其临床意义。方法采用全自动生化分析仪检测485例急性脑梗死患者(脑梗死组)血清钙、镁离子及血糖浓度,并与对照组及治疗2周后进行比较。结果(1)脑梗死组血清钙、镁浓度明显低于对照组(P<0.001),血糖浓度则明显高于对照组(P<0.001);(2)脑梗死组治疗2周后血清钙、镁浓度升高,但仍低于对照组(P<0.01),血糖浓度降低,但也高于对照组(P<0.01);(3)脑梗死组病情越重,血清钙、镁浓度越下降,血糖浓度则越升高。结论血清钙、镁离子与血糖浓度变化与急性脑梗死患者病情有一定关系,它们的含量变化可作为判断其病情及评估其预后的一项指标,对急性脑梗死患者早期补充镁制剂对其治疗及预后具有重要临床意义。
Objective To investigate the changes of serum calcium, magnesium and blood glucose in patients with acute cerebral infarction and its clinical significance. Methods Serum levels of calcium, magnesium and blood glucose in 485 patients with acute cerebral infarction (cerebral infarction group) were detected by automatic biochemical analyzer and compared with the control group and 2 weeks after treatment. Results (1) Serum calcium and magnesium concentrations in cerebral infarction group were significantly lower than those in control group (P <0.001), blood glucose concentration was significantly higher than that in control group (P <0.001); (2) (P <0.01); (3) The more severe the disease, the lower the serum calcium and magnesium concentrations in cerebral infarction group , The higher the blood glucose concentration. Conclusions The changes of serum calcium, magnesium and blood glucose are related to the condition of patients with acute cerebral infarction. The changes of their contents may be used as an index to judge their condition and assess the prognosis of patients with acute cerebral infarction. And the prognosis has important clinical significance.