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对致死性中线肉芽肿进行了组织病理、电镜观察、细胞表型研究及 DNA 分析,发现损害中的瘤细胞具有外周 T 细胞淋巴瘤的特征,认为本病实质上就是一种外周 T 细胞淋巴瘤,并与其它几种面部中线破坏性疾病组成了一个病谱,属于这一病谱的疾病可能包括特发性中线肉芽肿、Wegener 肉芽肿、中线恶性网状细胞增生症(多形性网状细胞增生症)、淋巴瘤样内芽肿及鼻部淋巴瘤等.本病最新命名——中线外周 T 细胞淋巴瘤.
The pathological, electron microscopic, cell phenotype, and DNA analysis of lethal midline granuloma revealed that the tumor cells in the lesion had the characteristics of peripheral T-cell lymphoma. It is considered that the disease is essentially a peripheral T-cell lymphoma. , and with a number of other destructive diseases of the midline of the face constitute a spectrum, diseases that may belong to this spectrum may include idiopathic midline granulomas, Wegener granulomas, and midline malignant reticulocytosis (polymorphic reticulation Cell hyperplasia), lymphoma-like cysts, nasal lymphoma, etc. The disease is newly named - midline peripheral T-cell lymphoma.