澳大利亚西部出生缺陷登记1980年建立,记录了全区域行产前诊断者和6岁以内儿童的出生缺陷。神经管缺陷(NTD)的患病率从1995—1999年前的近0.20%下降到最近5年的0.14%。目的是回顾分析澳大利亚西部出生缺陷登记在叶酸一级预防NTD中的作用。登记的数据对澳大利亚西部建立NTD发病 Registration of birth defects in western Australia was established in 1980 and records birth defects in prenatal diagnosis and in children up to 6 years of age in the entire region. The prevalence of neural tube defects (NTDs) decreased from nearly 0.20% before 1995-1999 to 0.14% for the last 5 years. The purpose was to review the role of registration of birth defects in western Australia in the prevention of NTD by folic acid. Registered data establish NTD incidence in western Australia