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观察了鳖甲煎丸对实验性肝硬化的治疗作用。应用四氯化碳造模后选取血清谷丙转氨酶（ALT）活性、透明质酸（HA）、血清白蛋白（A）及组织学变化作为测定指标并与秋水仙碱作比较，进行实验。实验结果：①2个剂量的鳖甲煎丸组ALT活性及HA含量明显下降，A含量明显增加。②组织学变化：2个剂量鳖甲煎丸治疗组肝细胞炎症反应明显轻于对照组；肝纤维化程度也比模型对照组轻。表明鳖甲煎丸能抑制纤维增生，促进胶原纤维降解吸收，改善肝功能，对实验性肝硬化有治疗作用。
The therapeutic effect of Biejiajian Pills on experimental liver cirrhosis was observed. After the model was established with carbon tetrachloride, serum alanine aminotransferase (ALT) activity, hyaluronic acid (HA), serum albumin (A), and histological changes were used as measurement indexes and compared with colchicine for experiments. Experimental results: The ALT activity and HA content of the 12 doses of Biejiajian Pill group decreased significantly, while the A content increased significantly. 2 Histological changes: The hepatocyte inflammatory response of the two doses of Biejiajian Pills was significantly lighter than that of the control group; the degree of hepatic fibrosis was also lighter than that of the model control group. It shows that Biejiajianwan can inhibit fiber proliferation, promote the degradation and absorption of collagen fibers, improve liver function, and have therapeutic effects on experimental liver cirrhosis.