目的前列地尔治疗糖尿病周围神经病变的疗效观察。方法选择60例该院收治的糖尿病患者,将其分为对照组和治疗组,每组有患者30例。对照组采用常规的饮食控制和药物降糖等治疗,治疗组在常规治疗的基础上给予前列地尔治疗,对比两组患者的治疗效果。结果治疗组的治疗有效率为90.0%,对照组为76.7%,治疗组患者的治疗有效率要明显高于对照组患者的治疗有效率(P<0.05)。结论前列地尔治疗糖尿病周围神经病变的疗效显著,能有效地提高治疗的有效率,值得在临床上进行推广。 Objective To investigate the therapeutic effect of alprostadil on diabetic peripheral neuropathy. Methods Sixty patients with diabetes mellitus were selected and divided into control group and treatment group, 30 patients in each group. The control group was treated with conventional diet control and hypoglycemic drugs. The treatment group was treated with alprostadil on the basis of routine treatment, and the therapeutic effect was compared between the two groups. Results The treatment effective rate was 90.0% in the treatment group and 76.7% in the control group. The treatment effective rate in the treatment group was significantly higher than that in the control group (P <0.05). Conclusion Alprostadil treatment of diabetic peripheral neuropathy significant effect, can effectively improve the efficiency of treatment, it is worth in the clinical promotion.