笔者从理论上计算~(131)I-肿瘤细胞核人鼠嵌合单克隆抗体(chTNT)治疗的肺肿瘤患者周围医护人员和家属的辐射剂量,结合医护人员个人剂量监测仪测量的结果,探讨患者周围相关人员的辐射安全,现报道如下。一、对象与方法1.药物及主要仪器。~(131)I-chTNT 由上海美恩生物技术有限公司提供,放射性浓度370 MBq/ml,放化纯>95%,细菌内毒素一次注射量<150 EU。CRC-15R 活度计(CapintecInC NJ,美国),SPECT 仪(Marconi IRIX Ⅲ,Marconi Medicalsystems,Cleveland,OH,美国),CaSO_4(Tm)和 LiF(Mg,Ti) The author theoretically calculated ~ (131) I-tumor cell nuclear chimeric monoclonal antibody (chTNT) treatment of lung cancer patients around the radiation dose of health care workers and their families, combined with the personal dose monitoring of health care workers measured the results to explore the patients Radiation safety around the relevant personnel are reported below. First, the object and method 1. Drugs and major equipment. ~ (131) I-chTNT was provided by Shanghai Mein Biotechnology Co., Ltd. with a radioactive concentration of 370 MBq / ml and a radiochemical purity of> 95%. The bacterial endotoxin injection volume was <150 EU. CRC-15R activity meter (CapintecInC NJ, USA), SPECT instrument (Marconi IRIX III, Marconi Medicalsystems, Cleveland, OH, USA), CaSO 4 (Tm) and LiF (Mg, Ti)