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目的:探讨丹参酮-ⅡA联合甲钴胺治疗糖尿病周围神经病变的临床疗效。方法:将我院收治的86例糖尿病周围神经病变患者随机分为联合组与对照组(各43例),对照组患者应用甲钴胺,联合组联合应用丹参酮-ⅡA和甲钴胺,比较两组患者的治疗效果。结果:治疗后,两组的运动神经及感觉神经传导速度均较治疗前显著提高,且联合组治疗后的运动神经、感觉神经传导速度均显著高于对照组(P<0.05)。联合组的总有效率为81.40%,显著高于对照组的55.81%,P<0.05。结论:丹参酮-ⅡA联合甲钴胺治疗糖尿病周围神经病变能有效改善运动及感觉神经传导速度,提高治疗效果,值得推广。
Objective: To investigate the clinical efficacy of tanshinone-ⅡA combined with mecobalamin in the treatment of diabetic peripheral neuropathy. Methods: Totally 86 patients with diabetic peripheral neuropathy admitted to our hospital were randomly divided into combined group and control group (43 cases in each group), while in control group, mecobalamin was used. In combination group, tanshinone-ⅡA and mecobalamin were used in combination. Group of patients treatment effect. Results: After treatment, the motor nerve and sensory nerve conduction velocity were significantly increased in both groups, and the motor nerve and sensory nerve conduction velocity in the combined group were significantly higher than those in the control group (P <0.05). The total effective rate was 81.40% in the combined group, significantly higher than that in the control group (55.81%, P <0.05). Conclusion: Tanshinone-ⅡA combined with mecobalamin can effectively improve the motor and sensory nerve conduction velocity and improve the therapeutic effect of diabetic peripheral neuropathy, which is worth promoting.