Disseminated herpes zoster in immunocompetent patients not due to varicella-zoster virus gene mutati

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To the editor:varicella-zoster virus (VZV) exclusively infects humans,causing varicella and herpes zoster (HZ).It is primary infection that varicella characteristically occurs early in life.However,VZV can reactivate,typically after the age of 50 years,to cause HZ.HZ is common due to a variety of factors such as age,fatigue,certain diseases and immunosuppressive therapy.Despite the chief reason that it has been reported also as immunocompromised states,disseminated herpes zoster (DHZ) with generalized eruption occurs only about 1% in HZ.1 Here we report two cases of DHZ in immunocompetent patients and a result of identification for VZV strain genotype.
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