为了避免阿司匹林对胃粘膜的刺激作用,国外已有肠溶衣阿司匹林片生产。作者用未包衣的阿司匹林片作对照,评价了肠溶衣阿司匹林片的临床效果。当单独一次给药1克时,未包衣的阿司匹林片在1小时内其血清水杨酸盐浓度即达到显著水平,持续3小时后逐渐下降;而肠溶衣阿司匹林片在6小时后其血清水杨 In order to avoid the stimulation of gastric mucosal effects of aspirin, enteric-coated aspirin tablets have been produced abroad. The authors used uncoated aspirin tablets as a control and evaluated the clinical effect of enteric-coated aspirin tablets. When administered at a single dose of 1 g, the uncoated aspirin tablet reached a significant level of serum salicylate concentration within 1 hour and gradually decreased after 3 hours; whereas the enteric coated aspirin tablet had serum salicylate levels after 6 hours Salisbury