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回顾1975~1991年间收治的254例上颌窦癌患者在不同治疗情况下,包括放疗、化疗、手术,单纯或综合治疗下的局部控制和生存情况。病例随访5年或至死亡,失访者按死亡计。统计学方法用U检验。结果:本组总的局部控制率为59.1%,Ⅱ、Ⅲ、Ⅳ期分别为71.4%、60.5%和54.6%,以R+S,A+R+S的局部控制率为最高,分别为80.0%和92.0%。治疗失败原因多为局部复发。总的3、5年生存率分别为44.1%,35.0%,Ⅱ、Ⅲ、Ⅳ期的5年生存率分别为53.6%、35.3%、30.9%。R+S和A+R+S的5年生存率为54.0%、56.0%,较其它治疗方法为高。上颌窦癌的治疗以计划性的综合术前放、化疗加手术的疗效为最好,早期发现和局部控制是治疗成功的关键。
A retrospective review of 254 patients with maxillary sinus cancer admitted between 1975 and 1991 under different treatment conditions, including local control and survival under radiotherapy, chemotherapy, surgery, simple or comprehensive treatment. Cases were followed up for 5 years or until death, and those who lost their lives were counted as dead. Statistical methods using U test. Results: The total local control rate was 59.1% in this group, 71.4%, 60.5% and 54.6% in stage Ⅱ, Ⅲ and Ⅳ, respectively. The local control rates of R + S and A + R + S were the highest .0% and 92.0%. Most of the reasons for the failure of treatment of local recurrence. The overall 3-year and 5-year survival rates were 44.1% and 35.0% respectively. The 5-year survival rates in stage II, III and IV were 53.6%, 35.3% and 30.9%, respectively. The 5-year survival rates of R + S and A + R + S were 54.0% and 56.0%, respectively, which were higher than other treatments. The treatment of maxillary sinus cancer in a planned integrated preoperative radiotherapy and chemotherapy plus the best effect of surgery, early detection and local control is the key to the success of the treatment.